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Important information about the supply of Creon 40,000


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Support Team

We would like to let you know that Mylan, the company that makes Creon, will not be making Creon 40,000 from June 2019. This is because they can't get enough of the enzymes used to make the 40,000 capsules. These are different to the enzymes used for the 10,000 and 25,000 capsules. The 10,000 and 25,000 capsules will still be available, and the company will now be making more of these. There is currently supply of Creon 40,000 available, so this change will happen in the next few months.


If you take Creon 40,000 at the moment, you can still get enough enzymes using Creon 25,000 which are slightly smaller capsules. For example:


if you normally take one 40,000 capsule, take two 25,000 capsules

if you normally take two 40,000 capsules, take three 25,000 capsules

if you normally take three 40,000 capsules, take five 25,000 capsules.


Creon capsules are interchangeable, therefore we advise that you speak with your healthcare professional regarding transferring to a different strength capsule to achieve the required dose. You should not be concerned about the efficacy when moving from one strength capsule to a different strength capsule.


If you have any worries about the changes in enzyme supplements available, or how to change from taking the 40,000 capsules, speak to our specialist nurses on our Support Line: https://www.pancreaticcancer.org.uk/speaktoanurse.


For more information, visit https://www.pancreaticcancer.org.uk/latest-news/2019/february/information-about-the-supply-of-creon-40-000/ you can also read more about pancreatic enzyme supplements here: https://www.pancreaticcancer.org.uk/information-and-support/diet-and-pancreatic-cancer/pancreatic-enzyme-supplements/.


Best wishes,

Pancreatic Cancer UK Support Team

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