Jump to content

Folfirinox minus Irinotecan


Recommended Posts

Hi all

Wondering if anyone has any experience of getting Folfirinox minus Irinotecan.

Since the beginning of my chemo (have had 5 2 week cycles) I have had issues which my Oncologist is confident are adverse reactions to Irinotecan. These start in the clinic when they administer it present themselves as flu like systems (on one occasion), D&V and incredibly painful stomach spasms, nausea etc. They tried flowing down the administration from a half hour to 1 hour with multiple Atripine injections both in the clinic and as back up when going home .

As I am tolerating the other drugs well they have decided that the best course of action is to remove this drug from the mix. This happened for the first time on cycle 4 with immediate benefit. I went from all the issues above plus terrible fatigue to being out and about on day 2 with only minor manageable side effects. I have lost 5 stone in 8 months but now my weight is stable.

My question is this...has anyone else had this drug dropped from the mix and if so what was the impact in terms of fighting the cancer. My a oncologist feels that it won't make a big difference and balanced with quality of life it's the way to go. I am hoping she is right but obviously want to be throwing everything at this.

Any experiences you have to share will be gratefully received.

Marie X

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue. By using our forums you agree to our Terms of Use and Privacy Policy.