A forum to focus on treatment related issues and side effects from treatment

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J_T
Posts: 954
Joined: Sun Mar 24, 2013 8:15 am

Re: Folfirinox and effects

Postby J_T » Tue Jul 23, 2013 12:32 pm

Hi Brian, really hoping the week off treatment has allowed Michelle to rally a little. Let us know how you get on tomorrow.

Julia x

Brian
Posts: 13
Joined: Mon Jul 01, 2013 8:52 pm

Re: Folfirinox and effects

Postby Brian » Thu Jul 25, 2013 10:28 am

Hi, Michelle had her appointment with her oncologist yesterday and it was agreed that she would continue with a break from chemotherapy for another three weeks. The oncologist did say that it was difficult to determine whether Michelle's weak and tired state was caused by the chemotherapy or the cancer. We asked for hormonal tablets to try to stimulate appetite as the previously prescribed steroids have had no effect at all and have now been prescribed Megestrol.
Also Michelle has an appointment for a CT scan next Wednesday which will indicate how effective the Folfirinox has been.
Thanks to all of you for your messages of support.
Brian

Cathy
Posts: 788
Joined: Fri Mar 15, 2013 5:43 pm

Re: Folfirinox and effects

Postby Cathy » Thu Jul 25, 2013 10:50 am

Hi Brian

My partner is doing really well on his break, it's done him the world of good so fingers Xd for Michelle and for next week. Keep in touch and let us know how you are getting on.

Kind regards

Cathy x

Brian
Posts: 13
Joined: Mon Jul 01, 2013 8:52 pm

Re: Folfirinox and effects

Postby Brian » Thu Jul 25, 2013 8:46 pm

Thanks Cathy, that's great to hear. I will let you know how things go and I hope it continues to go well for your hubby.
Brian

Brian
Posts: 13
Joined: Mon Jul 01, 2013 8:52 pm

Re: Folfirinox and effects

Postby Brian » Thu Jul 25, 2013 8:47 pm

I'm sorry Cathy, I should have said your partner. My apologies.
Brian

J_T
Posts: 954
Joined: Sun Mar 24, 2013 8:15 am

Re: Folfirinox and effects

Postby J_T » Thu Jul 25, 2013 10:07 pm

Hi Brian, here's hoping the rest from treatment will help Michelle feel stronger. It certainly seems the sensible thing to do.

Take care

Julia x

Support Team
Site Admin
Posts: 129
Joined: Fri Sep 23, 2005 3:50 pm

Re: Folfirinox and effects

Postby Support Team » Mon Aug 12, 2013 5:26 pm

Due to technical problems earlier I am having to repost this message from Brian. Sorry about this. Anna, Support Team.

Re: Folfirinox and effects
by Brian » Mon Aug 12, 2013 10:21 am
I am delighted to say that the break from chemotherapy has made a great deal of difference for Michelle. Over the last two weeks she has regained more energy and strength and also her appetite has improved. In fact she actually said one day that she felt hungry....I was so happy I almost cried. She's having breakfast, lunch and and a dinner again....maybe not the same quantity as before but that doesn't matter. We have managed to go out for walks twice a day and that has helped both of us. She had a scan two weeks ago and we have an appointment with the oncologist on Wednesday to hear the result and subsequently discuss what the next steps are.
Brian

Bee
Posts: 219
Joined: Fri May 03, 2013 9:39 pm

Re: Folfirinox and effects

Postby Bee » Mon Aug 12, 2013 10:49 pm

Hi Brian,
Really delighted to hear your wife has benefitted from the break in treatment. Sounds like you have been able to enjoy some lovely time together.
Good luck with the appointment n Wednesday, fingers crossed
Bee x

Cathy
Posts: 788
Joined: Fri Mar 15, 2013 5:43 pm

Re: Folfirinox and effects

Postby Cathy » Tue Aug 13, 2013 10:33 am

Yippee!!

That is great news Brian. Let's hope you have equally great news about the scan.

So now hopefully Michelle will go back to treatment feeling much stronger and with spirits raised.

Cathy xx

J_T
Posts: 954
Joined: Sun Mar 24, 2013 8:15 am

Re: Folfirinox and effects

Postby J_T » Tue Aug 13, 2013 12:08 pm

So very pleased to hear this news, Brian. I've been wondering how Michelle was getting on.

Hoping she kerps on the upward curve.

Julia x

Brian
Posts: 13
Joined: Mon Jul 01, 2013 8:52 pm

Re: Folfirinox and effects

Postby Brian » Sun Oct 20, 2013 4:02 pm

Hi,
Michelle was put forward for a clinical trial but this entailed eating a vast fatty breakfast, which I would struggle to eat and the Professor said would be too much for him, and take about 20 tablets a day. So it really wasn't suitable for Michelle.
Michelle then developed a large blood clot running the length of the Portacath tube across her chest, this resulted in the swelling of her face and neck and breathlessness and as a result I had to call the paramedics and she was admitted to hospital and when she was discharged she has to have a daily injection of blood thinner by the District Nurses.
It was then suggested by her Oncologist to come off the Filfirinox and start Chemotherapy of Carboplatin. She has had 2 sessions of Carboplatin and this has been less rigorous for her and she hasn't been vomiting.
Does anyone else know of Carboplatin?
Brian

Cathy
Posts: 788
Joined: Fri Mar 15, 2013 5:43 pm

Re: Folfirinox and effects

Postby Cathy » Sun Oct 20, 2013 4:35 pm

Hi Brian

Nice to hear from you again. It sounds like Michelle is doing ok by and large? You may have gathered if you have been keeping a track of this forum that blood clotting is a fairly common occurrence in pancreatic cancer. Jonathan had one as have a number of the others. If you felt you wanted the freedom from the district nurses each day and you were feeling confident, you could give Michelle the injections yourself. It's quite straightforward to do. The nurses would probably show you if you asked them.

There is a link here with info about the drug Michelle is on.

http://www.macmillan.org.uk/Cancerinfor ... latin.aspx

It's a platinum based drug and I know from our experience that one of the possible side effect, tingling in fingers and toes, can be cumulative. Now the weather is getting cooler Michelle might benefit from nice warm gloves and socks.

Is this still a trial? I ask as I couldn't find anything much in relation to pancreatic cancer although have read somewhere that there was a bit of a move towards using a breast cancer chemotherapy drug for PC.

Keep us posted and I do hope that this suits Michelle more and that she does well on it.

Kind regards

Cathy xx

Brian
Posts: 13
Joined: Mon Jul 01, 2013 8:52 pm

Re: Folfirinox and effects

Postby Brian » Mon Nov 11, 2013 10:12 pm

Dear all, Michelle developed an infection and became jaundiced on Thursday 24th October and urgently had to be admitted to Accident and Emergency for intravenous antibiotics and fluids. She was stabilised and scheduled to have a stent fitted on Tuesday 29th October. However, Michelle's veins collapsed and she was in pain as they attempted to insert lines for platelets. They were unsuccessful and when I visited that morning the nurse and doctor advised me of the situation and it was agreed that all medical care would stop and Michelle would be made comfortable. I spoke to Michelle and told her that there would be no more taking of blood, no more needles or pain and she immediately became more relaxed and relieved.
She had visits from family and friends and was able to smile and laugh again for the first time in 7 months as we recounted happy memories. Michelle gave a final smile and then passed away in the afternoon on Tuesday 5th November with myself and our two children present.
Michelle was a wonderful, courageous and strong woman who fought so hard to beat this horrible disease and even though she twice overcame breast cancer having had a lumpectomy and a mastectomy in the past 15 years, she couldn't beat pancreatic cancer.
My thanks to everyone on the forum for their support over these long and difficult six months.
Regards
Brian

Bee
Posts: 219
Joined: Fri May 03, 2013 9:39 pm

Re: Folfirinox and effects

Postby Bee » Mon Nov 11, 2013 10:34 pm

Hi Brian,
So sorry to hear of your loss, but it sounds like Michelle was calm and relaxed with her family by her side which is lovely. I wish you well and hope you all have lots of support around you.

Take care

Bee x

J_T
Posts: 954
Joined: Sun Mar 24, 2013 8:15 am

Re: Folfirinox and effects

Postby J_T » Mon Nov 11, 2013 11:27 pm

Dear Brian, I am so sad to hear of your loss. I know Michelle had a difficult time during her illness and I know how hard it is to watch the person you love suffer so much. May she rest in peace.

So many have left us recently, its just too sad.

Much love to you and your children.

Julia x