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Re: Concerned husband

Posted: Fri May 11, 2018 8:45 am
by PCUK Nurse Dianne
Good morning Saxon,

Good to hear that your wife has been able to continue on treatment and I am sure she may be looking forward to a short break from chemotherapy, maybe an opportunity to have some time away from hospitals and all that it involves.

If you have any further information about the PARP inhibitor, please do come back to us and we can do some research for you, there are quite a few research trials taking place, so it is a little difficult to appreciate exactly what this is at present.

Hopefully you are able to enjoy the lovely weather and a 'chemo break' for a while Saxon whilst waiting for CT scan results, of course we all understand this can also be an anxious time.

All best wishes,

Dianne
Pancreatic Cancer Specialist Nurse
Pancreatic Cancer UK
Support Phone line: 0808 801 0707
Email: nurse@pancreaticcancer.org.uk

Re: Concerned husband

Posted: Tue May 22, 2018 8:00 am
by Saxon
Morning!

We've had some good news back from the latest scan results. They are now showing a 25% reduction in the main tumour and some reduction in the secondary's on the liver. This means that she is now eligible for the PARP inhibitor trial - I've been sent a link from this site and it is the POLO one - it's the Olaparib drug? Anything further than what's on the link would be appreciated.

It is a blind placebo trial with a 3:2 ratio - as we've been led to believe. We are also investigating the opportunities to fund this drug ourselves to ensure that we get the real drug and not the chalk alternative.

She's developed an allergy to one of the chemo drugs and has been suffering with nausea, so is being prescribed more steroids both pre and post chemo to counteract these effects. she's having to set alarms on her phone to remind her which drugs to take and when as there are now so many.

Re: Concerned husband

Posted: Tue May 22, 2018 2:41 pm
by PCUK Nurse Rachel R
Hi Saxon

That is great news to hear. You must both be extremely pleased with that outcome.

In terms of the POLO trial I have a couple of other links here for you to look at. I wasn't sure if you have seen these. To be honest there is probably not a great deal more information contained within them but they may be useful. It would be good to possibly touch base with one of the contacts contained in the links if you have further specific questions.

http://www.cancerresearchuk.org/about-c ... pread-polo

https://www.clinicaltrials.gov/ct2/show ... =GB&rank=2

You are also very welcome to call support line to talk through any other queries, the telephone number is in the signature below.

With kindest wishes

Rachel

Rachel Richardson
Pancreatic Cancer Specialist Nurse
Support Team
Pancreatic Cancer UK
email: nurse@pancreaticcancer.org.uk
support line: 0808 801 0707

Re: Concerned husband

Posted: Tue May 22, 2018 7:26 pm
by Veema
Great news that the tumours are reducing...but I have to say, that good as trials are, I wouldn't want to risk getting the placebo, especially as the chemo she is currently on seems to be working well.

Good luck with whatever you decide.

Vx

Re: Concerned husband

Posted: Fri Jun 15, 2018 6:58 am
by Saxon
Thanks for the responses. Not been in a good place recently, so not been logging on much.

My wife has 1 chemo treatment left out of 12. It's really taking it's toll on her, so will be glad to finish that. The tumour markers have gone up again a little (we don't get told the actual figures so that we don't obsess over them) and my wife has been getting some of the original symptoms back, so like everyone says we're riding that roller coaster.

We have an appointment to see the specialists and discuss the parp inhibitors in the next few weeks, so will have to wait and see what the results of that are.

Re: Concerned husband

Posted: Fri Jun 15, 2018 2:34 pm
by PCUK Nurse Jeni
Hello Saxon,

Thanks for the update.

Sorry to hear things are not great at the moment. Your wife has done amazingly to tolerate the chemo so far - it gets tougher as the cycles go on.

I am sure that once that is finished, they will do an updated CT scan.

I hope the appointment goes well next week.

Please do not hesitate to contact us if we can help at all.

Kind regards,

Jeni.
Pancreatic Cancer Specialist Nurse
Support Team
Pancreatic Cancer UK
email: nurse@pancreaticcancer.org.uk
support line: 0808 801 0707

Re: Concerned husband

Posted: Mon Jun 18, 2018 5:57 pm
by Proud Wife
Good luck to you and your wife Saxon for your appointment with the specialists x